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. Author manuscript; available in PMC: 2013 Jun 20.
Published in final edited form as: Ren Fail. 2010;32(9):1103–1108. doi: 10.3109/0886022X.2010.504912

Figure 3.

Figure 3

Effects of high-glucose PDS and glutathione on mitochondrial ROS production of HPMC monolayer. (a) Representative photomicrographs viewed under a fluorescent microscope for mitochondrial ROS (MitoSOX red) (×600) and (b) quantification of ROS ratios (n = 3) after 24 h of incubation with tested media. Mitochondrial ROS significantly increased induced by high-glucose PDS. Glutathione could partially reverse the changes. *p < 0.05 versus control; **p < 0.01 versus 4.25% PDS group. A, Control: DMEM; B, 1.5% glucose PDS; C, 4.25% glucose PDS; and D, glutathione + 4.25% PDS.