Table 2. Operons associated with a FNR ChIP-seq peak and lacking a FNR-dependent change in expression in GMM but are activated by FNR in the presence of NO3 −, NO2 −, NarL or NarP (Category 3) according to Constantinidou et al. [19].
| Peak Center (nt)a | First Gene of Operon Downstreamb | B-number of First Gene in Operonc | Cellular Functiond | Impact of NO3 −, NO2 −, NarL or NarP on FNR Regulatione |
| 816075 | moaA | b0781 | Molybdopterin Biosynthesis Protein A | Activated by FNR in NO3 − |
| 1185000 | pepT | b1127 | Peptidase T | Activated by FNR in NO2 − |
| 1545300 | fdnG | b1474 | Formate Dehydrogenase N | Activated by FNR in NO3 − and by NarL |
| 2301675 | napF | b2208 | Periplasmic Nitrate Reductase | Activated by FNR in NO3 −, NO2 − and by NarP |
| 2619000 | upp | b2498 | Uracil Phosphoribosyltransferase | Activated by FNR in NO2 − |
| 3538050 | feoA | b3408 | Ferrous Iron Transport Protein | Activated by FNR in NO3 − |
| 4131675 | katG | b3942 | Hydroperoxidase I | Activated by FNR in NO3 − and NO2 − |
| 4360558 | cadC | b4133 | Metal-Sensitive Transcriptional Activator | Activated by FNR in NO3 − |
| 4460925 | nrdD | b4238 | Ribonucleoside-Triphosphate Reductase | Activated by FNR in NO3 − and NO2 − |
a
Genomic location within each FNR ChIP-seq peak with the highest read count (the summit of the peak).
b
First gene of the operon downstream of the FNR ChIP-seq peak, and operon designation was obtained from EcoCyc [70].
c
Identification number (B-number) for the first gene in each operon, obtained from EcoCyc [70].
d
Functional description of the products of the operons, obtained from EcoCyc [70].
e
Growth conditions (presence of NO3 −, NO2 −, NarL or NarP) in which FNR activated the operon, according to [19].