Table 4. Operons associated with a FNR ChIP-seq peak and lacking a FNR-dependent change in expression in GMM but are repressed by Fur (Category 4).
Peak Center (nt)a | First Gene of Operon Downstreamb | B-number of First Genec | Cellular Functiond | Referencee |
611865 | fes | b0585 | Enterochelin Esterase | [151], [152] |
621417 | fepD/entS | b0590/b0591 | Ferric Enterobactin Transporter (fepD)/Enterobactin Efflux Transporter (entS) | [152]–[154] |
623975 | fepB/entC | b0592/b0593 | Ferric Enterobactin Transporter (fepB)/Isochorismate Synthase (entC) | [152], [155], [156] |
1298775 | oppA | b1243 | Oligopeptide Transporter | [152] |
1308975 | tonB | b1252 | Iron-Siderophore Transport | [152], [157] |
1634625 | nohA | b1548 | Predicted Packaging Protein (Qin Prophage) | [152], [158] |
1735575 | purR | b1658 | Hypoxanthine Transcriptional Repressor | [159], [160] |
3150150 | exbB | b3006 | Iron-Siderophore Transport | [152] |
3273150 | garP | b3127 | Galactarate/Glucarate/Glycerate Transporter | [152], [160] |
3538050 | feoA | b3408 | Ferrous Iron Transport | [59] |
Genomic location within each FNR ChIP-seq peak with the highest read count (the summit of the peak).
First gene of the operon downstream of the FNR ChIP-seq peak, and operon designation was obtained from EcoCyc [70]. For peaks located within divergent promoters with both operons repressed by Fur, both genes are identified, separated by “/”.
Identification number (B-number) for the first gene in each operon, obtained from EcoCyc [70]. For peaks located within divergent promoters with both operons repressed by Fur, both B-numbers are identified, separated by “/”.
Functional description of the products of the operons, obtained from EcoCyc [70]. For peaks located within divergent promoters with operons repressed by Fur, the functions of both operons are listed, separated by “/”.
Reference for Fur repression of each operon.