Table 5. Operons lacking a FNR ChIP-seq peak but with a FNR-dependent change in expression in GMM that are known to be regulated through the action of the small regulatory RNA FnrS (Category 6).
Operona | B-number of First Geneb | Cellular Functionc | FNR Regulationd |
gpmA | b0755 | 2,3-Bisphosphoglycerate-Dependent Phosphoglycerate Mutase | Repressed |
cydDC | b0887 | Glutathione/Cysteine Transporter | Repressed |
chaA | b1216 | Sodium/Proton Antiporter | Repressed |
adhP | b1478 | Ethanol Dehydrogenase/Alcohol Dehydrogenase | Repressed |
sodB | b1656 | Iron-Containing Superoxide Dismutase | Repressed |
yobA-yebZY | b1841 | Conserved Protein | Repressed |
dld | b2133 | Lactate Dehydrogenase | Repressed |
folE-yeiB | b2153 | GTP Cyclohydrolase I | Repressed |
eco | b2209 | Ecotin Homodimer/Serine Protease Inhibitor | Repressed |
folX-yfcH | b2303 | Dihydroneopterin Triphosphate 2-Epimerase | Repressed |
yggG | b2936 | Predicted Metallopeptidase | Repressed |
Operon showing a statistically significant FNR-dependent change in expression compared to WT but lacking a FNR ChIP-seq peak upstream. Operon definitions obtained from EcoCyc [70].
Identification number (B-number) for the first gene in each operon, obtained from EcoCyc [70].
Cellular function of the product of the operon, obtained from EcoCyc [70].
FNR regulation of each operon as identified in the transcriptomic experiments performed in this study.