Table 2. Incidence and relative risk (RR) of cardiac ischemia with bevacizumab according to tumor types.

	No. ofStudies	Cardiac ischemia (No./Total N0.) Bevacizumab	Cardiac ischemia (No./Total N0.) Control	Incidence(95% CI), %	RR(95% CI)
Overall	7	41/2417	13/2200	1.0 (0.6–1.4)	2.49 (1.37–4.52)
Colorectal Cancer	4	33/1957	13/1779	1.1 (0.5–1.8)	2.13 (1.11–4.06)
Renal cell Carcinoma	2	7/438	0/387	0.8 (0.2–1.4)	6.12 (0.83–45.43)
Liver Cancer	1	1/22	0/34	–	4.57 (0.19–107.29)

Abbreviation and notes: CI, confidence interval. The incidence and RR were calculated from the trials included in this study by meta-analysis as described in the “Method” section.