Table 1.

Between-treatment differences in body composition and serum markers

Variable	OLETF SED (n=7)	LETO SED (n=6)
Body composition variables
Bodyweight (g)	693 ± 14	474 ± 19***
DXA bfat (%)	37.0 ± 1.6	14.9 ± 0.6***
Lean mass (g)	435 ± 8	407 ± 17
fat mass (g)	257 ± 15	72 ± 5***
Serum markers
Glucose (mg/dl)	290 ± 14	151 ± 5***
Insulin (mg/dl)	6.2 ± 0.6	2.8 ± 0.6**
HDL-c (mg/dl)	33 ± 2	26 ± 1*
LDL-c (mg/dl)	50 ± 7	61 ± 4
Triglycerides (mg/dl)	319 ± 47	40 ± 5***
Plasma adipokines
Leptin (ng/ml)	102 ± 11	13 ± 2***
IL-1β (pg/ml)	17 ± 13	ND
IL-6 (pg/ml)	825 ± 222	ND
IL-10 (pg/ml)	927 ± 332	34 ± 10*
IL-12p70 (pg/ml)	125 ± 66	12 ± 5
TNF-α (pg/ml)	8.9 ± 4.2	3.9 ± 1.9
MCP-1 (pg/ml)	49 ± 10	56 ± 28
RANTES (pg/ml)	938 ± 69	1218 ± 334

All data are presented as mean ± SE.

Abbreviations: DXA bfat = dual x-ray absorptiometry body fat percentage, ND = not detectable;

^*indicate a significant difference between groups (p < 0.05),

^**indicate a significant difference between groups (p < 0.01),

^***indicate a significant difference between groups (p < 0.001).