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. 2013 Jun 20;8(6):e65762. doi: 10.1371/journal.pone.0065762

Table 1. Clinical outcomes of TKIs on IM/SU-resistant GIST.

Administration Studies N SD>6 months PFS (months) OS (months)
Best supportive care Italiano [26] 18 11% 2.1 2.4
Nilotinib Italiano [26] 67 35% 4.1 11.8
Cauchi [31] 13 7% 2.0 N.A.
Montemurro [29] 52 47% 3 8.5
Kim [30] 17 47% 5.9 18.5
Sawaki [25] 35 29% 3.8 10.3
Sorafenib Italiano [26] 55 42% 4.9 10.7
Park [27] 31 36% 4.9 9.7
Kindler [28] 32 32% 5.2 11.6
Dasatinib Trent [32] 47 21% 3.8 10.3

S.D.: stable disease; PFS: progression-free survival; OS: overall survival; N.A: not available.