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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2013 Aug 1;63(4):428–437. doi: 10.1097/QAI.0b013e31828ac85f

TABLE 2.

In situ hybridization signals for cellular and pathogen RNAs in macaque HiLNs

Uninfected Acute Clinical latency AIDS
6202 7102 13402 13502 5702 7402 6002 7902 13002 13102 5802 5902 7002 12402b 12602b 12802b
CXCL9/Mig ++a ++ ++ ++ ++ ++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++
CXCL10/IP-10 + ++ ++ + ++ ++ +++ +++ +++ +++ +++ +++ +++ +++ +++ ++
CXCL11/I-TAC + + + + + + +++ +++ ++ +++ +++ + +++ +++ +++ ++
CCL2/MCP1 +/− + ++ + ++ ++ +++ +++ +++ +++ +++ ++ +++ +++ +++ +++
CCL3/MIP-1α + + + +/− + + +++ +++ ++ +++ +++ ++ +++ +++ ++
CCL5/RANTES ++ ++ + +++ +++ +++ +++ +++ +++ +++ +++
CCL20/MIP-3α +++ +++ +++ ++ +++ +++ +++ +++ ++ +++ + +/− + ++ + ++
CCL21/6Ckine +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++
IFN-γ +/− +/− + + +/− ++ +++ ++ ++ + + ++ +++ ++ ++
IL-10 + + + + + ++ ++ ++ ++ ++ ++ + ++ +++ +++ ++
P.carinii ndc nd nd nd nd nd +++ ++ +++
SIV +++ +++ + +++ +++ ++ + ++ + ++
a

ISH was performed with antisense and control sense 35S-labeled riboprobes specific for the indicated host gene-specific mRNA, SIV mRNA, or P. carinii rRNA. -, no signal detected; +/-, rare mRNA+ cells in entire tissue section; +, 1-5 mRNA+ cells per 200X field; ++, 6-10 mRNA+ cells per 200X field; +++, >10 mRNA+ cells per 200X field.

b

These three macaques had clear histologic evidence of severe P. carinii pneumonia (PCP), as detailed in ref. 5.

c

nd, not done.