Figure 1. HDACs in cardiac hypertrophy.
Class I HDACs participate in pressure overload-induced pathological cardiac hypertrophy. HDAC inhibition can prevent load-induced hypertrophy and reverse pre-existing hypertrophy.
Class I HDACs participate in pressure overload-induced pathological cardiac hypertrophy. HDAC inhibition can prevent load-induced hypertrophy and reverse pre-existing hypertrophy.