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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Hepatology. 2013 Apr 17;58(2):810–818. doi: 10.1002/hep.26323

Figure 3. Effects of mTOR inhibition on liver physiology and metabolism.

Figure 3

This figure illustrates the different targets of mTOR, and how mTOR inhibitors affect the various metabolic and physiologic processes in the liver, leading to decreased cell survival and autophagy, decreased protein and lipid synthesis, and decreased ribosomal biogenesis.