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. 2013 Jun 20;8(6):e65486. doi: 10.1371/journal.pone.0065486

Figure 4. Marker of protein nitration.

Figure 4

Plasma levels of 3-nitrotyrosine (A, B) and 3-nitrotyrosine/L-Dopa ratio (C, D) in Apo-E−/− mice following acute (A, C) or chronic (B, D) radiation exposure. Mean ± SEM. Acute, 0 (n = 3), 0.5 Gy (n = 8), 2 Gy (n = 4). Chronic, 0 (n = 4), 2 Gy (n = 4). 3-nitrotyrosine: Two-way ANOVA with Dose (0, 2 Gy) and Time (acute, chronic) as factors, Dose main effect, p = 0.004. *Tukey test, 0 vs 2 Gy, p<0.05. 3-nitrotyrosine/L-DOPA: Two-way ANOVA with Dose (0, 2 Gy) and Time (acute, chronic) as factors, Dose X Time, p = 0.025. *Tukey test, 0 vs 2 Gy, p<0.05. +Tukey test, acute vs chronic, p<0.05.