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. 2013 Jun 18;8(6):e65889. doi: 10.1371/journal.pone.0065889

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© 2013 Samykutty et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Boyden chamber assay shows that control LNCaP and PC-3 prostate cancer cells have a greater number of migrated cells while LNCaP and PC-3 samples treated with 60 µM and 75 µM piperine show fewer migrated cells in Transwell® chambers. Arrow indicates migrated cells. The inhibition of cell migration suggests that piperine may have anti-migratory properties in prostate cancer. Data shown here is representative of one of three similar results obtained.