Table 2. Up-regulated plasma membrane receptors identified from the over-represented canonical pathways shown in Figure 5.
Ingenuity Canonical Pathways | −log(p-value)* | Plasma membrane receptors |
Clathrin-mediated Endocytosis Signaling | 2.58E00 | LDLR,ITGA5,TFRC |
Caveolar-mediated Endocytosis Signaling | 2.15E00 | ITGAV,ITGA5 |
NF-κB Activation by Viruses | 2.12E00 | ITGAV,ITGA5 |
Virus Entry via Endocytic Pathways | 1.99E00 | ITGA5,TFRC |
Role of Wnt/GSK-3β Signaling in the Pathogenesis of Influenza | 9.57E-01 | FZD5 |
The P-value was calculated using Fischer's exact test determining the probability of the association between the genes in the canonical pathway.