Figure 5. Parasite Multiplication Rate following PfSPZ Challenge is comparable to mosquito-bite subjects with similar LBIs.

Figure shows relationship Between PMR and LBI for participants successfully infected with malaria in groups 1–3 (green crosses), compared to historical data from mosquito bite CHMI trials undertaken at our centre involving malaria naïve unvaccinated subjects (blue dots), and malaria naïve ChAd63-MVA ME-TRAP vaccinated subjects (red dots). These data were obtained using the linear model; results were similar with the sine model (data not shown).