Table 3. The comparison of bacterial community in LSCC group, normal tissue adjacent to tumor group, and control group at the levels of phyla and genera.

	Cancer – Adjacent	Cancer – Control	Adjacent – Control
	p value*	p value§	p value†
Phyla
Firmicutes	0.37	0.004	0.051
Fusobacteria	0.09	0.001	0.14
Bacteroidetes	0.59	0.11	0.04
Proteobacteria	0.81	0.73	0.56
Actinobacteria	0.78	0.03	0.02
Genera
Streptococcus	0.33	<0.001	0.002
Fusobacterium	0.09	0.002	0.17
Prevotella	0.41	0.04	0.005
Neisseria	0.33	0.46	0.78
Gemella	0.98	0.17	0.15

^*The comparison of bacterial composition between LSCC tumor group and normal tissue adjacent to tumor group; ^§ the comparison of bacterial composition between LSCC tumor group and control group; ^† the comparison of bacterial composition of normal tissue adjacent to tumor group and control group. p value were analyzed from Student t-test and matched to Figure 5.