Table 4. The bacterial composition of 15 genera were significantly different between the laryngeal cancer and control groups.
| Cancer group | Control group | p value* | |
| Genera | % | % | |
| Rothia | 0.8 | 4.2 | <0.001 |
| Streptococcus | 25.1 | 56.1 | |
| Fusobacterium | 19.1 | 7.9 | |
| Prevotella | 15.0 | 6.9 | |
| Gemella | 4.4 | 2.2 | |
| Granulicatella | 0.9 | 0.5 | |
| Peptostreptococcus | 3.6 | 0.6 | |
| Parvimonas | 4.6 | 1.3 | |
| Peptostreptococcaceae incertae sedis | 0.5 | 0.04 | |
| Porphyromonas | 1.0 | 2.0 | |
| Catonella | 0.7 | 0.2 | |
| Treponema | 0.5 | 0.1 | |
| Bulleidia | 0.02 | 0.1 | |
| Selenomonas | 0.5 | 0.04 | |
| Burkholderia | 0.03 | 0.003 |
*
PLS-DA, LOOCV and MANOVA analyses were applied to investigate the bacterial composition between the laryngeal cancer and control groups. Fifteen genera probably were related to LSCC disease.