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. 2013 Jun 18;8(6):e66885. doi: 10.1371/journal.pone.0066885

Figure 7. MSO accelerated kindled seizures.

Figure 7

MSO (5, 10, and 20 µg in 2 µl) was injected into the ipsilateral DG on the first day after kindled seizures progressed to stage 2. (A) behavioral stage progression of seizures, (B) AD duration, (C) generalized seizure duration, (D) numbers of stimulations required to reach stage 5 from MSO administration, (E) numbers of stimulations required to retain in stage 0–3 and stage 4 in kindling acquisition, (F) difference of ADT between just before drug administration and on the third day after administration (saline group, n = 6; MSO groups, n  =  9/group). G shows the electrographic examples of afterdischarge recorded from the ipsilateral amygdala in four groups on the third day after drug administration. ES represents electrical kindling stimulation. Data are shown as mean ± S.E.M. *P<0.05, ** P<0.01 and *** P<0.001 compared with the saline group. ### P<0.001, as compared with each other.