Figure 1. Precisions of a direct interaction transfer to S. cerevisiae for the different experimental settings.

We show six eukaryotic species having the largest number of interactions. For the all interaction setting (allI) only the occurrence of a transferred interaction in the S. cerevisiae network is required, whereas for the genetic (GenI) and physical (PhyI) interaction setting also the exact type of the transferred interaction is checked. In addition to the precisions, the number of total transferred interactions and consistent interactions for each species and type is shown on top of the corresponding bar. Most interactions can be transferred from S. pombe to S. cerevisiae. There the transfer precision is highest for physical and genetic interactions. For the allI setting the highest transfer precision is observed for M. musculus to S. cerevisiae. This is due to the small number of interactions, which are mostly involved in conserved biological processes like DNA replication and chromosome organization.