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. 2013 Jun 18;8(6):e66635. doi: 10.1371/journal.pone.0066635

Table 1. Protein interaction networks.

Species Interactions
Genes Physical Genetic Other Total Total interactions
per gene
S. cerevisiae 6,328 55,767 104,926 17,674 178,367 28.19
H. sapiens 28,383 43,412 71 20,992 64,475 2.27
D. melanogaster 14,321 19,088 2,118 17,265 38,471 2.69
S. pombe 4,958 1,943 9,665 804 12,412 2.5
C. elegans 20,184 5,483 1,785 4,208 11,476 0.57
M. musculus 24,865 3,513 3 2,596 6,112 0.25
A. thaliana 26,496 5,048 67 937 6,052 0.23
P. falciparum 5,503 2,215 0 4 2,219 0.4
R. norvegicus 24,770 804 0 867 1,671 0.07
D. rerio 24,352 173 11 13 197 0.01

Overview of protein interaction networks extracted from the database iRefIndex [33] for the ten eukaryotic model species with the largest protein interaction networks. Besides the total number of protein interactions, the number of physical, genetic and interactions with an unknown interaction type is given. Only the interaction network of S. cerevisiae, H. sapiens, D. melanogaster and S. pombe have more than 2 interaction per gene (S. cerevisiae peaks with 28.19).