Table 3. NICD1 staining in peripheral T cell lymphomas.
Tumor Type (N=55 Total Cases) | NICD1 Staining Results | ||
---|---|---|---|
Angioimmunoblastic lymphoma (N=14) | 86% positive (N=12; all subset positive) | ||
Peripheral T cell lymphoma, NOS (N=12) | 42% positive (N=5; all subset positive) | ||
Cutaneous T cell lymphoma (N=12) | 17% positive (N=2; all subset positive) | ||
Anaplastic large cell lymphoma (ALCL, N=7) | 14% positive (N=1; subset positive, ALK+ tumor) | ||
86% negative (N=6, 1 ALK+ tumor, 5 ALK-tumors) | |||
Adult T cell leukemia/lymphoma (N=5) | 20% positive (N=1; diffusely positive) | ||
EBV+ T/NK extranodal lymphoma (N=4) | 0% positive | ||
Subcutaneous paniculitis-like T cell lymphoma (N=1) | 0% positive |
NOS, not otherwise specified; ALK, anaplastic lymphoma kinase; EBV, Epstein–Barr virus; NK, natural killer cell
Diffusely positive, ≥80% of cells positive; subset positive, ≤80% of cells positive