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. 2013 Jun 18;8(6):e68637. doi: 10.1371/journal.pone.0068637

Figure 7. Adipose-conditioned medium suppresses the development of human breast mammospheres in culture.

Figure 7

A: Average size of mammospheres formed by hMECs from the breast tissue of two donors after 3 days of culture in fresh or adipocyte-conditioned medium. Columns represent average size ± SEM of 60 mammospheres measured in each group. ***Statistically significant difference (p ≤ 0.001). B: Light microscopy of representative mammospheres formed by hMECs in 3D Matrigel culture with fresh or adipose-conditioned medium. Bar = 100 µm.