Figure 3.

Kinetics of serum cytokines and chemokines in DCs-depleted and non-depleted mice during the course of S. pneumoniae infection. DCs-depleted (white symbols) and non-depleted (black symbols) CD11c-DTR chimera mice were challenged intranasally with 1 × 10⁸ CFU of S. pneumoniae D39 and the levels of IL-6 (A), IFN-γ (B), KC (C), IP-10 (D), and MCP-1 (E) in serum were determined by multiplex technology at 24, 48, and 72 h after bacterial inoculation. Each symbol represents the mean ± SD of the compilation of three independent experiments. ^*p < 0.05.