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. 2013 Jul 10;19(2):102–114. doi: 10.1089/ars.2012.4626

FIG. 9.

FIG. 9.

Oligonol inhibited AOM plus DSS-induced mouse colon carcinogenesis. (A) Effects of oligonol on body weight changes in mice treated with AOM+DSS. (B) Comparison of the colon length at 8 weeks. Results are expressed as means±SD (n=10 each group). (C) A representative photograph of the mouse colon in each group. The incidence and the multiplicity of colonic adenomas. For (A) and (B), data are expressed as means±SE (n=10, in each group), *p<0.05. (D) Macroscopic view of the mouse colon in each group. (E) Histopathology of colonic dysplasia. (a) Control; (b) AOM+DSS; (c) AOM+DSS+Oligonol (0.5 mg/kg); (d) AOM+DSS+Oligonol (5 mg/kg); (e) Oligonol (5 mg/kg) alone. Animal treatment and other experimental conditions are described in the Materials and Methods section. Magnifications×200.