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Simulated photocurrents of an amphibian rod stimulated by flashes of light of increasing intensity. The duration of each flash is 24 ms, and each stimulus leads to 1.54, 46, 280, 985, 30 400, and 115 000 photoisomerizations of rhodopsin. The mathematical model used for the simulation is the one reported in ref (57) in which the Ca2+-relay mechanism has been implemented as described here.
