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. Author manuscript; available in PMC: 2013 Jun 21.
Published in final edited form as: Acad Emerg Med. 2010 Jul;17(7):741–747. doi: 10.1111/j.1553-2712.2010.00790.x

Table 2.

LOD of the Most Common Meningitis-causing Bacteria Using Our Broad-based PCR

Organisms CFU/mL
S. pneumoniae 70
S. aureus 50
L. monocytogenes 110
N. meningitides 20
H. influenza 10
E. coli* 30
S. epidermidis 10

CFU = colony-forming units; CSF = cerebrospinal fluid; LOD = limit of detection; PCR = polymerase chain reaction.

*

E. coli was tested by spiking organism in both sterile CSF and water. The LOD was comparable for both. Due to limited supply of pooled negative CSF, other organisms were spiked in molecular grade water to test for the LOD.