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Steady state slow inactivation.
| pH 7.4 Control | pH 7.4 (10 μM) Ranolazine | pH 7.4 (100 μM) Ranolazine | pH 6.0 Control | pH 6.0 (10 μM) Ranolazine | pH 6.0 (100 μM) Ranolazine | |
|---|---|---|---|---|---|---|
| V1/2 | −89 ± 3# | −95 ± 3 | −113 ± 1*# | −71 ± 1# | −87 ± 2* | −104 ± 4*# |
| z | 21 ± 3 | 17 ± 2 | 13.3 ± 0.2*# | 16.6 ± 0.4 | 20 ± 2 | 25 ± 3*# |
| n | 13 | 9 | 7 | 13 | 9 | 8 |
Statistically different from control (p < 0.05).
Statistically different between pH conditions (p < 0.05).
