Table 3.
Immunohistochemical Staining of Prostaglandin Synthesizing Enzymes in Ocular Tissues
| Cyclooxygenase-2 | Prostaglandin E Synthase | Prostaglandin D Synthase | |
|---|---|---|---|
| Conjunctiva | |||
| Epithelium | ↑ | ↑ | ↑ |
| Stroma | — | — | — |
| Cornea | |||
| Epithelium | ↑ | — | — |
| Stroma | — | — | — |
| Endothelium | — | — | — |
| Lacrimal gland | |||
| Acina | ↑ ↑ | — | — |
| Ductal epithelium | ↑ | — | — |
| Periductal infiltrating cell | — | ↑ | — |
| Meibomian gland | |||
| Acina | ↑ | — | ↓* |
| Ductal epithelium | — | — | — |
↑ = elevated expression compared with normal control; — = not detected; ↑ ↑ = extensively elevated expression compared with normal control.
*
Especially decreased staining at nucleus.