Arteriolar resistance vessel remodeling in the myocardium. Values are means (SD). A and B, Arteriolar LD (A); arteriolar length, total arteriolar length (B). Arteriolar LD and arteriolar length were calculated using previously described methods (19). Arteriolar LD (millimeters per cubic millimeter) = Σ(a/b)/M, where a and b are the maximum and minimum external arteriolar diameters, and M is the tissue area. Arteriolar length = LD (millimeters per cubic millimeter) × LV weight per cubic millimeter; ∼1 mg of cardiac tissue is equivalent to 1 mm3) (n = 6/group). *, P < .05 vs control.