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. Author manuscript; available in PMC: 2013 Jun 21.
Published in final edited form as: Immunity. 2002 Aug;17(2):211–220. doi: 10.1016/s1074-7613(02)00365-5

Figure 1. Phenotypic Characterization of DTR Transgenic Mice.

Figure 1

(A) Schematic representation of the DTR/GFP transgene.

(B) Flow cytometric analysis of spleen cells of DTR transgenic (line 57) and nontransgenic FVB/N mice indicating GFP expression in CD11c+ DC. Histograms show GFP expression in CD8+ and CD8− DC subsets. Histogram gates are indicated in the dot plot. Open histograms, wild-type cells; filled histograms, DTR transgenic cells. Dead cells were excluded by propidium iodide (PI) staining.