Volume measurements from right and left cortex and hippocampus of Sprague and Wistar rats. There were no significant effects of Treatment, Strain, or Hemisphere, (nor any significant interactions) on cortex volume. There was a significant main effect of Strain on hippocampal volume, demonstrating that Wistar rats—across Treatment groups—had larger hippocampi than Sprague counterparts. However, the Kiaa0319 shRNA treatment was not found to have an impact on hippocampal volume.