Table 1.
Demographic data, MEQ score, habitual sleep timing, and chronobiologic measures for the two allelic groups: C and Non-C carriers; and the three genotypic groups: T/T, C/T, and C/C.
| p1 | n | C carriers (C/T and C/C) | n | Non-C carriers (T/T) | n | C/T | n | C/C | p2 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Age | 0.911 | 74 | 27.60 ± 12.60 | 105 | 27.40 ± 11.20 | 67 | 27.70 ± 13.00 | 7 | 26.30 ± 8.50 | 0.949 |
| ♂:♀ | na | 74 | 51:23 | 105 | 73:32 | 67 | 46:21 | 7 | 5:2 | na |
| Race (%Caucasian) | na | 74 | 77% | 105 | 73% | 67 | 73% | 7 | 100% | na |
| MEQ | 0.902 | 74 | 51.95 ± 12.80 | 105 | 52.20 ± 12.50 | 67 | 51.95 ± 13.00 | 7 | 52.00 ± 16.40 | 0.992 |
| Bedtime | 0.887 | 74 | 23:56 ± 1:30 | 105 | 23:54 ± 1:42 | 67 | 23:55 ± 1:30 | 7 | 24:11 ± 1:30 | 0.898 |
| Wake time | 0.543 | 74 | 8:15 ± 1:24 | 105 | 8:23 ± 1:30 | 67 | 8:18 ± 1:24 | 7 | 7:47 ± 1:12 | 0.557 |
| CBT phase | 0.334 | 42 | 5:19 ± 1:48 | 57 | 4:54 ± 2:18 | 37 | 5:28 ± 1:48 | 5 | 4:09 ± 1:47 | 0.263 |
| CBT phase angle | 0.174 | 42 | 2.90 ± 1.20 | 57 | 3.28 ± 1.50 | 37 | 2.80 ± 1.20 | 5 | 3.64 ± 0.55 | 0.171 |
| CBT period | 0.262 | 30 | 24.18 ± 0.20 | 39 | 24.13 ± 0.20 | 28 | 24.18 ± 0.20 | 2 | 24.21 ± 0.21 | na |
| Melatonin phase | 0.752 | 40 | 22:54 ± 1:42 | 48 | 22:30 ± 2:00 | 35 | 22:57 ± 1:42 | 5 | 22:35 ± 1:59 | 0.925 |
| Melatonin phase angle | 0.053 | 40 | 1.28 ± 0.80 | 48 | 1.72 ± 1.10 | 35 | 1.37 ± 0.80 | 5 | 1.78 ± 1.10 | 0.149 |
| Melatonin period | 0.203 | 29 | 24.21 ± 0.20 | 39 | 24.15 ± 0.20 | 27 | 24.21 ± 0.20 | 2 | 24.16 ± 0.20 | na |
NOTE: Mean ± standard deviation. Bedtimes, wake times, and phase measures for both CBT and melatonin are listed as clock hour. CBT phase angle is calculated as the difference between CBT nadir and habitual wake time/lights on; melatonin phase angle is the difference between DLMO25% and habitual bedtime/lights off. P1 values denote comparisons between allelic groups (C vs. Non-C carriers) and p2 values are from comparisons among the genotypes (T/T, C/T, and C/C).