Fig. 1.

Time course of the changes in serum 25(OH)D₃ (panel a), 24,25(OH)₂D₃ (panel b), and 1,25(OH)₂D₃ (panel c) levels in vitamin D₃ deficient (filled circle), insufficient (open circle), and sufficient (filled square) CRC patients receiving 2000IU of oral cholecalciferol daily. Vitamin D₃ status stratification based on baseline serum 25(OH)D₃ levels: deficient < 20 ng/mL (N = 9), insufficient 20 to 31.9 ng/mL (N = 24) and sufficient ≥ 32ng/mL (N = 17). Panels d, e, and f show plots (and correlation coefficients) of serum 25(OH)D₃ versus 24,25(OH)₂D₃, 25(OH)D₃ versus 1,25(OH)D₃, and 24,25(OH)₂D₃ versus 1,25(OH)D₃ levels at baseline and during D₃ supplementation. Caption in panel a, also refers to panels b and c