Schematic illustration of our simulations. pRFs estimated from the full-field condition (three examples in panels A–C, top) and the stimulus sequence from the scotoma condition were entered in the “forward solution” to obtain simulated fMRI responses (black lines and circles). For the purpose of this illustration, the time dimension is ignored; stimulus and response are plotted as a function of eccentricity. Two methods were then used to recover the pRF parameters from the simulated fMRI responses: the full-stimulus pRF method, where the full-field stimulus was used as input to the pRF fitting procedure, and the effective-stimulus pRF method, where the scotoma is modeled in the stimulus representation. The bottom rows show the recovered pRFs with the two methods (red and green, respectively) together with the original pRFs (blue).