Table 2.
Polysomnographic report: patients with and without CPAP treatment
| |
Overlap syndrome |
|
COPD |
|
|
||
|---|---|---|---|---|---|---|---|
|
n = 22 |
|
n = 22 |
|||||
| Baseline | With CPAP | P | Baseline | With CPAP | P | †P | |
| Total sleep time (minutes) |
294.3 ± 80.5 |
290.1 ± 94.9 |
0.758 |
287.8 ± 77.9 |
273.2 ± 71.7 |
0.408 |
0.760 |
| Sleep efficiency (%) |
67.2 ± 12.8 |
68.6 ± 14.3 |
0.833 |
66.3 ± 14.2 |
65.2 ± 12.9 |
0.650 |
0.699 |
| AHI event. h-1 |
39.2 ± 16.5 |
4.6 ± 2.9 |
0.001 |
7.5 ± 4.1* |
1.6 ± 1.4 |
0.001 |
0.001 |
| ODI event. h-1 |
20.4 ± 16.2 |
3.1 ± 2.9 |
0.001 |
3.1 ± 2.2* |
0.9 ± 1.1 |
0.001 |
0.001 |
| Average SaO2% |
93.3 ± 2.2 |
94.5 ± 1.7 |
0.011 |
93.8 ± 2.0 |
94.9 ± 2.1 |
0.001 |
0.866 |
| Lowest SaO2% |
80.3 ± 8.8 |
89.3 ± 3.9 |
0.001 |
87.0 ± 4.6* |
90.2 ± 4.3 |
0.005 |
0.089 |
| Wake% |
26.6 ± 10.3 |
21.8 ± 13.7 |
0.211 |
25.5 ± 14.2 |
26.9 ± 12.7 |
0.578 |
0.124 |
| N1% |
23.0 ± 14.0 |
15.4 ± 8.9 |
0.010 |
20.3 ± 14.1 |
16.5 ± 8.7 |
0.079 |
0.296 |
| N2% |
39.5 ± 12.6 |
41.2 ± 14.9 |
0.700 |
34.0 ± 11.8 |
33.2 ± 11.6 |
0.941 |
0.751 |
| N3% |
2.3 ± 3.9 |
5.2 ± 6.1 |
0.001 |
7.5 ± 9.4 |
9.2 ± 11.4 |
0.235 |
0.191 |
| REM% |
8.5 ± 7.1 |
16.4 ± 10.3 |
0.004 |
12.2 ± 7.7 |
13.9 ± 7.5 |
0.144 |
0.026 |
| CPAP pressure (cm H2O) | 6.8 ± 1.8 | 4.9 ± 0.9* | |||||
*P < 0.05; when compared with baseline overlap syndrome group.
P values represent comparisons between baseline and with CPAP in each corresponding group.
†P values represent comparisons with regards to the changes with CPAP treatment between overlap syndrome and COPD in each corresponding group.
AHI apnoea/hypopnea index, ODI oxygen desaturation index, SWS slow wave sleep, REM rapid eye movement, CPAP continuous positive airway pressure.