Table 4.
Differentially expressed genes and their GO terms related to pigmentation and melanogenesis in black versus white sheep skin
| GO terms | Genes | Relative expression in black vs white sheep skin | Fold change | FDR p-value | Corrected p-value of GO term |
|---|---|---|---|---|---|
| Developmental pigmentation |
Tyrosinase |
Up-regulation |
96.88 |
1.89 × 10-137 |
0.00273 |
| G-protein coupled receptor 143 |
Up-regulation |
35.63 |
1.32 × 10-28 |
||
| Pallidin-like protein |
Down-regulation |
0.16 |
1.47 × 10-17 |
||
| P protein-like |
Up-regulation |
17.65 |
4.78 × 10-5 |
||
| Melanophilin |
Up-regulation |
27.75 |
1.94 × 10-158 |
||
| Pigment cell differentiation |
Pallidin-like protein |
Down-regulation |
0.16 |
1.47 × 10-17 |
1 |
| P protein-like |
Up-regulation |
17.65 |
4.78 × 10-5 |
||
| Melanophilin |
Up-regulation |
27.75 |
1.94 × 10-158 |
||
| Cellular pigmentation and pigment granule localization |
G-protein coupled receptor 143 |
Up-regulation |
35.63 |
1.32 × 10-28 |
1 |
| Melanophilin |
Up-regulation |
27.75 |
1.94 × 10-158 |
||
| Pigment metabolic process involved in developmental pigmentation and pigmentation |
Tyrosinase |
Up-regulation |
96.88 |
1.89 × 10-137 |
1 |
| G-protein coupled receptor 143 |
Up-regulation |
35.63 |
1.32 × 10-28 |
||
| P protein-like |
Up-regulation |
17.65 |
4.78 × 10-5 |
||
| Melanin metabolic process | Aralkylamine N-acetyltransferase (AANAT) |
Up-regulation |
9.80 |
7.9 × 10-5 |
1 |
| Chain E, Crystal Structure Of The 14-3-3 Zeta:serotonin N- Acetyltransferase |
Up-regulation |
7.84 |
1.44 × 10-6 |
||
| Tyrosinase |
Up-regulation |
96.88 |
1.89 × 10-137 |
||
| P protein-like |
Up-regulation |
17.65 |
4.78 × 10-5 |
||
| Membrane-associated transporter protein-like isoform 1 |
Up-regulation |
32.75 |
1.03 × 10-42 |
||
| Membrane-associated transporter protein-like isoform 2 | Up-regulation | 4099.12 | 3.46 × 10-13 |