Table 2.
mRNA expression of stem cell makers in human lung cancer and non-cancer lung tissues
| |
Lung cancer |
Non-cancer |
P |
Lung cancer |
Non-cancer |
P |
|---|---|---|---|---|---|---|
| Positive rate, %(n) | Positive rate, %(n) | Expression, χ ± s | Expression, χ ± s | Value | ||
| Bmi1 |
88.4(99/112) |
66.7(12/18) |
0.026 |
0.60±0.73 |
0.32±0.29 |
0.118 |
| CD133 |
85.7(96/112) |
55.6(10/18) |
0.006 |
0.77±0.90 |
0.58±0.97 |
0.057 |
| CD44 |
98.2(110/112) |
88.9(16/18) |
0.092 |
1.67±1.77 |
1.44±1.33 |
0.606 |
| Sox2 |
98.2(110/112) |
83.3(15/18) |
0.019 |
2.06±2.15 |
0.99±1.53 |
0.001 |
| Nanog |
63.4(71/112) |
33.3(6/18) |
0.016 |
0.23±0.42 |
0.04±0.09 |
0.013 |
| OCT4 |
85.7(96/112) |
38.8(7/18) |
<0.0001 |
0.46±0.50 |
0.12±0.27 |
<0.0001 |
| Msi2 | 96.4(108/112) | 94.4(17/18) | 0.531 | 1.29±1.13 | 0.47±0.51 | <0.0001 |