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. 2013 Jun 21;8(6):e67027. doi: 10.1371/journal.pone.0067027

Figure 3. Effect of chronic morphine treatment and naloxone precipitated morphine withdrawal on neuropeptide expression in the hypothalamus.

Figure 3

Mean (±SEM) values of relative expression values of selected hypothalamic neuropeptide mRNAs in placebo or morphine treated rats two hours after saline or naloxone injection. Neuropeptide mRNA levels were normalised to GAPDH levels and expressed as fold change compared to the levels of placebo implanted saline groups set to 1. n = 6/group, *p<0.0.1 compared to saline injected respective controls.