Table 2. Mean±SEM plasma hormone concentrations in placebo- or morphine implanted and pair-fed rats 2 or 7 days after pellet implantation.
2 days | 7 days | |||||
Placebo | Morphine | Pair Fed | Placebo | Morphine | Pair Fed | |
ACTH (pM) | 8,05±4,02 | 22,35±11,52 | 20,80±5,16 | 49,20±18,43 | 34,87±3,57 | 59,05±15,76 |
CORT (nM) | 128,1±94,1 | 1365,4±443,7* + | 282,5±129,3 | 515,2±365,1 | 1622,5±937,4 | 1682,5±325,6 |
PRL (ng/ml) | 6,06±2,38 | 4,10±1,58 | 6,60±2,73 | 5,32±1,33 | 7,85±3,98 | 17,57±3,90 |
p<0,05 morphine vs. pair fed; + p<0,05 placebo vs. morphine; n = 7/group.