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. 2013 Jun 21;8(6):e66729. doi: 10.1371/journal.pone.0066729

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© 2013 Miyake et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Xi: X inactivation pattern based on the inactive X chromosome, Xa: X-inactivation pattern based on the active X chromosome. Mat: X chromosome inherited from the mother, Pat: X chromosome inherited from the father. Xi and Xa are differentiated by their methylation status at the androgen receptor gene locus. The maternal X and the paternal X are also differentiated by CAG repeat polymorphism at this locus. The X chromosome inactivation patterns showed no differences between the twins in lymphoblasts (A), skin fibroblasts (B), or hair cells (C).