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. 2013 Jun 21;8(6):e67115. doi: 10.1371/journal.pone.0067115

Figure 1. B. tropicalis allergens co-adsorbed with eLPS to alum induces a non-classical allergic airway disease phenotype.

Figure 1

C57BL/6 (WT) mice were sensitized twice with Bt or Bt plus eLPS co-adsorbed to alum and challenged twice with Bt. Control group consisted of non-manipulated animals. The experiments were performed 24 h after the last Bt challenge. Same protocol was performed using OVA as allergen. Total bronchoalveolar lavage (BAL) leukocyte counts (A); Eosinophils (B) and neutrophils (C) counts in the BAL fluid; Effects of eLPS dose response on eosinophils (D) and neutrophils (E) counts in the BAL fluid, total (F) and Bt-specific (G) IgE in serum; Representative lung sections staining with periodic acid-Schiff (PAS) showing normal lung histology in control group (left), Bt group (middle), Bt/LPS group (right), and Mucus index (H). Results are expressed as mean ±SEM for groups of five mice and are representative of two experiments. *Significant difference (p<0.05) when compared with the control group or as indicated.