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. 2013 Jun 21;8(6):e67126. doi: 10.1371/journal.pone.0067126

Figure 6. Hyperglycemic conditions decrease the mitochondrial membrane integrity.

Figure 6

A–C: Representative flow cytometry histogram showing JC-1 staining after treatment with low glucose, high glucose and CCCP-treatment (positive control). D. Graph showing significant reduction of mitochondrial membrane integrity in cells treated with high glucose. The arbitrary units indicate the ratio of red/green fluorescence. The shift from red to green indicates the mitochondrial membrane depolarization.