Table 2. Sequence Similarity Comparison of AD-related proteins, between Humans and species of rodent: Sequence Similarity Scores and Sequence Identity (%) shown for each gene.
APP | PSEN1 | PSEN2 | BACE1 | ADAM10 | APOE | IDE | MAPT* | |
Guinea Pig | 1269 (97%) | 759 (96%) | 761 (96%) | 1001 (97%) | 1316 (96%) | 416 (70%) | 1880 (97%) | 655 (90%) |
Mouse | 1261 (97%) | 740 (93%) | 764 (96%) | 1009 (96%) | 1308 (96%) | 442 (71%) | 1848 (96%) | 652 (89%) |
Rat | 1269 (97%) | 743 (92%) | 745 (95%) | 1010 (96%) | 1313 (96%) | 410 (70%) | 1849 (96%) | 660 (90%) |
The MAPT sequence of guinea pig was predicted.