Table 2. Identified DEGs involving in adipogenesis, signaling pathway, and lipid metabolism.
Gene | Full Name | Tissues expressed | Reference |
ADIPOQ | adiponectin, C1Q, and collagen domain containing | I(−) | Wang et al 2009 [22] |
BMP2 | bone morphogenetic proteins 2 | O(−) | Rosen and MacDougald 2006 [63] |
BMP4 | bone morphogenetic proteins 4 | S(−) | Rosen and MacDougald 2006 [63] |
CDK6 | cyclin-dependent kinase 6 | I(+) | Sarruf et al 2005 [64] |
CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | I(+) | Rosen and MacDougald 2006 [63] |
DDIT3 | DNA-damage-inducible transcipt 3 (CHOP) | I(+) | Darlington at al 1998 [65] |
DGAT1 | diacylglycerol acyltransferase | I(−) | Jeong et al 2012 [54] |
EBF1 | early B-cell factor 1 | O(−) | Akerblad et al 2002 [66] |
EGR2 | early growth response 2 | I(+), S(−) | Chen et al 2005 [67] |
FABP4 | fatty acid binding protein4 | I(−) | Michal et al 2006 [68] |
FAS | Fas (TNF receptor superfamily, member 6) | I(+) | Wang et al 2009 [22] |
FASN | fatty acid synthase | I(−), S(+) | Jeong et al 2012 [54] |
FGF1 | fibroblast growth factor 1 | O(+) | Hutley et al 2004 [69] |
FGF2 | fibroblast growth factor 2 | S(−) | Kawaguchi et al 1997 [70] |
FOXC2 | forkhead box C2 | I(+) | Rosen and MacDougald 2006 [63] |
GATA2 | GATA binding protein 2 | I(+) | Tong et al 2000 [71] |
KLF5 | Kruppel-like factor 5 | S(−), I(+) | Oishi et al 2005 [72] |
KLF6 | Kruppel-like factor 6 | I(+), O(−) | Li et al 2005 [73] |
KLF7 | Kruppel-like factor 7 | I(+) | Kanazawa et al 2005 [74] |
LPL | lipoprotein lipase | O(+), I(−) | Jeong et al 2012 [54] |
PPARG | peroxisome profiliferator-activated receptor, gamma | I(−) | Rosen and MacDougald 2006 [63] |
PPARGC1A | peroxisome proliferator activated receptor gamma, coactivator 1 alpha | O(−) | Scime et al 2005 [75] |
THRSP | thyroid hormone responsive | O(+), I(−) | Wang et al 2009 [22] |
UCP1 | uncoupling protein 1 | O(+) | Rosen and MacDougald 2006 [63] |
UQCRC1 | ubiquinol-cytochrome c reductase core protein 1 | I(−) | Kunej et al 2007 [76] |
WNT10B | wingless-type MMTV integration site family, member 10B | O(−) | Longo et al 2004 [77] |
WNT5b | wingless-type MMTV integration site 5B | S(−) | Kanazawa et al 2005 [78] |
WNT6 | wingless-type MMTV integration site 6 | I(+) | Tseng et al 2005 [79] |
(+) : up-regulated.
(−) : down-regulated.