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. 2013 Jun 4;23(2):025105. doi: 10.1063/1.4808157

Figure 2.

Figure 2

Dose-dependent effects of Bcd and Cic on tll expression. (a) The Bcd activation gradient works against the inverse transcriptional repression gradient of Cic in activating many of its targets. (b) Quantification of the boundaries of anterior tll expression. (c) and (d) Quantified boundaries of the anterior tll in embryos with different levels of Bcd (c) and Cic (d). Averaged boundaries are shown with error bars indicating standard error of the mean (s.e.m). The numbers of embryos used in the analysis are N = 23 (bcd[6]), N = 95 (bcd[6]/+), N = 49 (wt), N = 42 (bcd[4x]), N = 65 (cic[1]), N = 56 (cic[1]/+), and N = 32 (cic[4x]). (e) These results are consistent with incoherent feedforward mechanism, where Bcd and Torso activate both tll and an anterior repressor of tll.