Table 2. Multivariate analysis of factors associated with recurrence after resection for HCC.
| Variable | Hazard ratio (95% confidence interval) | Standard error | p | |
| All patients (n = 333) | ||||
| ICG-15R >10% | 1.386 (1.036–1.854) | 0.148 | 0.028 | |
| GGT >60 U/L | 1.628 (1.210–2.190) | 0.151 | 0.001 | |
| Macroscopic venous invasion | 2.375 (1.650–3.425) | 0.186 | <0.001 | |
| Microscopic venous invasion | 1.499 (1.080–2.083) | 0.167 | 0.016 | |
| Without anti-viral therapy | 2.296 (1.451–3.632) | 0.234 | <0.001 | |
| Patients without antiviral therapy after resection (n = 271) | ||||
| HBV DNA >106 copies/mL | 1.428 (1.047–1.947) | 0.158 | 0.024 | |
| GGT >60 U/L | 1.700 (1.239–2.331) | 0.194 | 0.001 | |
| Macroscopic venous invasion | 2.387 (1.634–3.497) | 0.180 | <0.001 | |
| Microscopic venous invasion | 1.594 (1.121–2.273) | 0.195 | 0.010 | |
| Patients with available complete HBs gene sequence data but without anti-viral therapy (n = 216) | ||||
| Multi-nodularity | 1.693 (1.115–2.571) | 0.213 | 0.013 | |
| Macroscopic venous invasion | 2.415 (1.418–4.098) | 0.271 | 0.001 | |
| Cirrhosis | 1.544 (1.047–2.279) | 0.198 | 0.029 | |
| Edmondson stage III or IV | 1.526 (1.029–2.263) | 0.201 | 0.036 | |
| Pre-S deletion | 1.564 (1.057–2.314) | 0.200 | 0.025 | |
Abbreviations: ICG-15R, indocyanine green retention rate at 15 minutes; GGT, gamma-glutamyltransferase.