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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Eur J Haematol. 2013 May 3;91(1):62–68. doi: 10.1111/ejh.12118

Table 2.

Independent predictors of history of ACS or pneumonia from multiple logistic regression modeling.

OR (95% CI) P value
a. Hb SS (n= 318)1
History of asthma 3.9 (2.1-7.3) <0.0001
Age (years) 1.09 (1.03-1.14) 0.001
>3 severe pain episodes in last year 4.4 (1.9-10.1) 0.002
TRV (m/sec) 3.2 (1.1-9.1) 0.028
WBC (natural log) 2.03 (1.02-4.01) 0.043
b. Other genotypes (N=127)2
>3 severe pain episodes in last year 8.35 (1.72-40.58) 0.009
Hydroxyurea treatment 2.76 (1.06-7.23) 0.038
1

Variables entered into model: age, α-thalassemia status, number of blood transfusions, category of severe pain episodes, history of asthma, reticulocyte number, platelets, WBC count, ferritin, LDH, TRV.

Four outliers were removed.

2

Variables entered into model: hydroxyurea treatment, number of blood transfusions, number of severe pain episodes, ferritin.