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. Author manuscript; available in PMC: 2013 Jun 22.
Published in final edited form as: Vascul Pharmacol. 2010 Aug 12;53(0):193–199. doi: 10.1016/j.vph.2010.08.003

Figure 3. Effects of collar and lacidipine treatment on maximal contractile responses (Emax) to KCl and 5-HT.

Figure 3

A. Collar inhibited maximal contraction to KCl both in placebo and lacidipine group (*** P < 0.001, n=8, * P < 0.05, n=5, sham vs. collar, two way ANOVA, Bonferroni post test). Lacidipine treatment significantly inhibited maximal contraction to KCl (+++ P <0.001, Placebo vs. lacidipine, two way ANOVA, Bonferroni post test) only in sham arteries compared to placebo. B. Collar inhibited 5-HT-induced contractions in the placebo group (★ ★ ★ P < 0.001, n=7 sham vs. collar in placebo group, one way ANOVA) but not in lacidipine group. Lacidipine induced inhibition of 5-HT-induced contractions was significant only in sham arteries (xx P <0.01, n=5, placebo vs. lacidipine in sham arteries, one way ANOVA).