Table 1.
Genomic organization of human CerS
| CerS name | Other names | Chromosome location | Number of transcripts | Notes |
|---|---|---|---|---|
| CerS1 | Lass1/UOG1 | 19p12 | 2 | Transcript variant 1 includes GDF1 and a longer CerS1; transcript variant 1 has a shorter and distinct C-terminus |
| CerS2 | Lass2/TRH3 | 1q21.3 | 2 | Transcript variants encode the same protein, but variant 2 has an alternative splice site in the 5′-UTR |
| CerS3 | Lass3/T3I | 15q26.3 | 1 | – |
| CerS4 | Lass4/TRH1 | 19p13.2 | 1 | – |
| CerS5 | Lass5/TRH4 | 12q13.12 | 1 | – |
| CerS6 | Lass6/T1I | 2q24.3 | 1 | – |