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Kras G12D suppresses the Wnt/β-catenin pathway in T-ALL cells. WT thymocytes and bulk T-ALL cells were stained for the unphosphorylated (active) form of β-catenin. Purified mouse IgG1κ was used as an isotype control. Representative histograms from three independent experiments are shown. Positive cells are gated as illustrated. The percentages of positive cells are indicated on each plot. ***, p < 0.001.
