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In vivo effect of nilotinib on PLC5 xeonograft nude mice. A, tumor growth curves of PLC5. Points, mean (n = 6); bars, S.E. *, p < 0.05; **, p < 0.01. B, Western blot analysis of P-AMPK, AMPK, and LC-3 in PLC5 tumors. C, analysis of PP2A activity. Columns, mean; bars, S.D. (n = 6). *, p < 0.05 versus vehicle group.
